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Group
Members Chevelle Cason
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RESEARCH INTERESTS
Project 1: To
date, a detailed understanding of biofilm formation is lacking.
Current models
of the early stages of
biofilm adhesion do not account for chemical reactions that may
occur at the surface
of a substrate.
Our research is focused on
understanding the role of siderophores (organic ligands produced
by most bacteria that have a high binding affinity for iron) in
bacterial adhesion
to metal oxide surfaces.
Project 2: We are also evaluating protective (nonbiofouling) coatings for stainless steel medical implants. Collaborators: Dr. Hazel Barton ![]()
The Bullen Research Group also has a collaborative project with Dr. Martines, Dr. Russell, and Dr. Walters in investigating the use of custom dendrimers for drug delivery across the blood brain barrier (BBB). This project utilizes atomic force microscopy and ATR-FTIR to investigate penetration of dendrimers into model BBBs.
Selected
Publications H. A. Bullen, M. J. Dorko, J. K.
Oman, and S. J. Garrett "Valence and Core-Level Binding Energy Shifts in
Orpiment (As2S3), Realgar (As4S4)
and Pararealgar (As4S4) Arsenic Sulfide" Surf.
Sci. 2003, 531, 319. H. A. Bullen, S. J. Garrett "CrO2 by XPS: Comparison of CrO2 Powder to CrO2 films on TiO2(110) Single Crystal Surfaces" Surf. Sci. Spectra 2002, 8, 225. H. A. Bullen, S. J. Garrett “Epitaxial Growth of CrO2 Thin Films on TiO2(110) Surfaces” Chem. of Mater. 2002, 14, 243. Selected Presentations (* indicates undergraduates) W. L. Schmidt,* H. A. Bullen. “Catecholate siderophore complexation on metal oxide surfaces.” ACS National Meeting, Chicago, IL, March 2007. (Poster) R. A Wilson*, H. A. Bullen. “Surface modification of stainless steel medical implants for biofouling prevention.” ACS National Meeting, Chicago, IL, March 2007. (Poster) T. Fabre,* J. Hogan,* K. A. Walters, K. H. Martines, D. A. Tomalia, H. A. Bullen. “Design and characterization of drug delivery systems across the blood brain barrier.” ACS National Meeting, Chicago, IL, March 2007. (Poster) J. Hogan,* T. Fabre,* K. A. Walters, K. H. Martines, D. A. Tomalia, H. A. Bullen. “ATR-FTIR analysis of the interaction of biotinylated dendrimers with blood brain barrier models.” ACS National Meeting, Chicago, IL, March 2007. (Poster) S. Proctor,* H. A. Barton, H. A. Bullen. “Impact of pyoverdin siderophores extracted from Pseudomonas aeruginosa on bacterial adhesion to metal oxides.” ACS National Meeting, Chicago, IL, March 2007. (Poster) C. D. Girten,* Jody R. Helton,* D. A. Tomalia, K. H. Martines, H. A. Bullen, K. A. Walters. “Surface modification of G4 and G5 PAMAM Dendrimers” ACS National Meeting, Chicago, IL, March 2007. (Poster) H. A. Bullen, K. A. Walters. “Development of a nanomaterials one week intersession course at NKU.” ACS National Meeting, Chicago, IL, March 2007. (Talk) H. A. Bullen. “Open access peer review port for communicating chemistry: Analytical Sciences Digital Library.” ACS National Meeting, Chicago, IL, March 2007. (Talk) H. A. Bullen, R. A. Wilson, S. Proctor, W. Schmidt, P. J. Hogan, H. J. Stahl, M. Shields. “Probing biofilm formation: spectroscopic and scanning probe microscopy characterization of bacterial adhesion onto metal oxide surfaces.” Pittcon Conference, Chicago, IL, February 2007. (Poster) A. Bennett* H. A. Bullen, and H. A. Barton. “Improved Methods to Relate Metabolic Activities to Biogeochemical Signatures in Carbonate Rock.” CUR Posters at Hill, Washington D. C., April 2006. (Poster) A. Bennett,* H. A. Bullen, and H. A. Barton. “Improved Methods to Relate Metabolic Activities to Biogeochemical Signatures in Carbonate Rock” KAS Meeting, Richmond, KY, Nov. 2005. H. J. Gulley*, H. A. Bullen. “Impact of Aqueous-Metal Oxide Interfaces on Biofilm Formation: ATR-FTIR as an In-Situ Approach to Probe Bacterial Adhesion” ACS National Meeting, San Diego, CA, March 2005.
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