Welcome to
Robert J. Kempton's Home Page

Robert J. Kempton Regents Professor of Chemistry Email: Kempton@nku.edu Office: SC 450

Chemistry Northern Kentucky University Highland Heights, KY 41099 (859)572-5116

---

The courses I'm teaching this semester are:

CHE 310-002 organic chemistry lecture CHE 310L organic chemistry lab (M)
Course Number	Exams 1 and 2 from Fall, 08 (different text) 310, F08, 1-1.cdx.pdf 310, F08, 1-2.cdx.pdf 310, F08, 1-3.cdx.pdf 310, F08, 1-4.cdx.pdf 310, F08, 2-1.cdx.pdf 310, F08, 2-2.cdx.pdf 310, F08, 2-3.cdx.pdf 310, F08, 2-4.cdx.pdf
CHE 310-002
CHE 311 Organic Chemistry Lecture	082_311_002_RJK.pdf (311 lecture syllabus) Previous Exams 311, S2008, 1-1.cdx.pdf 311, S2008, 1-2.cdx.pdf 311, S2008, 1-3.cdx.pdf 311, S2008, 1-4.cdx.pdf 311, S2008, 2-1.cdx.pdf 311, S2008, 2-2.cdx.pdf 311, S2008, 2-3.cdx.pdf 311, S2008, 2-4.cdx.pdf 311, s2008, 3-1.cdx.pdf 311, s2008, 3-2.cdx.pdf 311, s2008, 3-3.cdx.pdf 311, s2008, 3-4.cdx.pdf 311, s2008, 4-1.cdx.pdf 311, s2008, 4-2.cdx.pdf 311, s2008, 4-3.cdx.pdf 311, s2008, 4-4.cdx.pdf 311, s2008, 4-5.cdx.pdf
CHE 311-L Organic Chemistry lab	082_311L_012_RJK.pdf (311 lab syllabus) Organic Chemistry Laboratory. Information about the lab is available on the department’s website.
CHE 410: Spectroscopy	082_410_001_RJK.pdf (syllabus)

Research Interest

Folic acid (1) is a vitamin which in its reduced form is involved in several cellular one-carbon transfer reactions, among them the conversion of 2'-deoxyuridine-5'-monophosphate (dUMP) into 2'-deoxythymidine-5'-monophosphate (dTMP).  Methotrexate (2), first introduced clinically in 1953 and still widely used in cancer chemotherapy, acts by inhibiting dihydrofolate reductase, the enzyme required for the reduction of folic acid.  My students and I are working on the synthesis of a number of analogues of Methotrexate.  Compound 3, an N-10 deaza analogue of Methotrexate, has recently been prepared in our laboratories.

---

NKU Home Page -- Help -- Comments -- WebDev -- ATS -- Disclaimer